A kit for the measurement of plasma ESM-1 concentrations
Special features
- Complete ELISA kit with pre-coated plates
- Rapid assay, takes less than 3 hours, less than 1 hour of hands-on-time
- Quantification of the ESM-1 in biological fluids (sera, plasma) or in human cell culture supernatants
- Ready to use assay
- For research use only. Not for use in diagnostic procedures.
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If you are interested in the Pregnostic®-PE Ip for research purposes in cooperation with IQ Products, please contact us!
Introduction
Endothelial cell-specific molecule (ESM-1) is a unique biomarker of vascular endothelial activation/dysfunction in diseases. The variation of blood levels of ESM-1 may reflect endothelial dysfunction in several pathological conditions, including sepsis, cancer, dengue fever and obesity 1. Higher ESM-1 levels are also related to occurrence of pre-eclampsia in pregnancy 2-6.
Recently IQ Products’ Research and Development team published, in cooperation with the University Medical Center Groningen (The Netherlands), their findings of the ESM-1 plasma levels during uncomplicated and pre-eclamptic pregnancies in Pregnancy Hypertension.
Product specifications
Pregnostic®-PE Ip contains all components required for quantification of human ESM-1 in cell culture supernatants, serum or plasma. This human Pregnostic®-PE Ip ELISA set uses the robust and well-described quantitative sandwich immunoassay technique. The kit is available for research purposes. The performance characteristics of this kit have not completely established yet.
References:
- Sarrazin et al. (2010) J Cancer Sci. Ther. 2: 47-52
- Schuitemaker et al. (2018) Pregnancy Hypertens. Mar 1;12:58-64
- Chang et al. (2015) Int J Clin Exp Pathol. 8(11): 14733-14740
- Adekola et al. (2015) J Matern Fetal Neonatal Med. 28(14):1621-1632
- Cakmak et al. (2016) Clin Exp Hypertens. 38(2): 137-142
- Hentschke et al. (2015) 74: 152-156